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mRNA translation and protein synthesis: an analysis of different modelling methodologies and a new PBN based approach

BACKGROUND: mRNA translation involves simultaneous movement of multiple ribosomes on the mRNA and is also subject to regulatory mechanisms at different stages. Translation can be described by various codon-based models, including ODE, TASEP, and Petri net models. Although such models have been exten...

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Detalles Bibliográficos
Autores principales: Zhao, Yun-Bo, Krishnan, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015640/
https://www.ncbi.nlm.nih.gov/pubmed/24576337
http://dx.doi.org/10.1186/1752-0509-8-25