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mRNA translation and protein synthesis: an analysis of different modelling methodologies and a new PBN based approach
BACKGROUND: mRNA translation involves simultaneous movement of multiple ribosomes on the mRNA and is also subject to regulatory mechanisms at different stages. Translation can be described by various codon-based models, including ODE, TASEP, and Petri net models. Although such models have been exten...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015640/ https://www.ncbi.nlm.nih.gov/pubmed/24576337 http://dx.doi.org/10.1186/1752-0509-8-25 |