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Translocation junctions in TCF3-PBX1 acute lymphoblastic leukemia/lymphoma cluster near transposable elements

BACKGROUND: Hematolymphoid neoplasms frequently harbor recurrent genetic abnormalities. Some of the most well recognized lesions are chromosomal translocations, and many of these are known to play pivotal roles in pathogenesis. In lymphoid malignancies, some translocations result from erroneous V(D)...

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Detalles Bibliográficos
Autores principales: Rodić, Nemanja, Zampella, John G, Cornish, Toby C, Wheelan, Sarah J, Burns, Kathleen H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015642/
https://www.ncbi.nlm.nih.gov/pubmed/24135088
http://dx.doi.org/10.1186/1759-8753-4-22