HIV-1 induces cytoskeletal alterations and Rac1 activation during monocyte-blood–brain barrier interactions: modulatory role of CCR5

BACKGROUND: Most HIV strains that enter the brain are macrophage-tropic and use the CCR5 receptor to bind and infect target cells. Because the cytoskeleton is a network of protein filaments involved in cellular movement and migration, we investigated whether CCR5 and the cytoskeleton are involved in...

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Detalles Bibliográficos
Autores principales: Woollard, Shawna M, Li, Hong, Singh, Sangya, Yu, Fang, Kanmogne, Georgette D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015682/
https://www.ncbi.nlm.nih.gov/pubmed/24571616
http://dx.doi.org/10.1186/1742-4690-11-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015682/
https://www.ncbi.nlm.nih.gov/pubmed/24571616
http://dx.doi.org/10.1186/1742-4690-11-20

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