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Fenofibrate induces apoptosis of triple-negative breast cancer cells via activation of NF-κB pathway

BACKGROUND: There are a lot of unmet needs in patients with triple-negative breast cancer (TNBC). Fenofibrate, a peroxisome proliferator-activated receptor alpha (PPAR-α) agonist, has been used for decades to treat hypertriglyceridaemia and mixed dyslipidaemia. Recent studies show that it might have...

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Detalles Bibliográficos
Autores principales: Li, Ting, Zhang, Qunling, Zhang, Jian, Yang, Gong, Shao, Zhimin, Luo, Jianmin, Fan, Minhao, Ni, Chen, Wu, Zhenhua, Hu, Xichun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015735/
https://www.ncbi.nlm.nih.gov/pubmed/24529079
http://dx.doi.org/10.1186/1471-2407-14-96