Cathepsin S-mediated autophagic flux in tumor-associated macrophages accelerate tumor development by promoting M2 polarization

BACKGROUND: Tumor-associated macrophages (TAMs) are the major component of tumor-infiltrating leukocytes. TAMs are heterogeneous, with distinct phenotypes influenced by the microenvironment surrounding tumor tissues, but relatively little is known about the key molecular in these cells that contribu...

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Detalles Bibliográficos
Autores principales: Yang, Min, Liu, Jingwei, Shao, Jianghua, Qin, Yanwen, Ji, Qunsheng, Zhang, Xiaolin, Du, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015740/
https://www.ncbi.nlm.nih.gov/pubmed/24580730
http://dx.doi.org/10.1186/1476-4598-13-43

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015740/
https://www.ncbi.nlm.nih.gov/pubmed/24580730
http://dx.doi.org/10.1186/1476-4598-13-43

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