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Methylglyoxal modulates endothelial nitric oxide synthase-associated functions in EA.hy926 endothelial cells

BACKGROUND: Increased levels of the sugar metabolite methylglyoxal (MG) in vivo were shown to participate in the pathophysiology of vascular complications in diabetes. Alterations of endothelial nitric oxide synthase (eNOS) activity by hypophosphorylation of the enzyme and enhanced monomerization ar...

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Detalles Bibliográficos
Autores principales: Su, Yang, Qadri, Syed M, Wu, Lingyun, Liu, Lixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015749/
https://www.ncbi.nlm.nih.gov/pubmed/24050620
http://dx.doi.org/10.1186/1475-2840-12-134