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Identification of parameter correlations for parameter estimation in dynamic biological models
BACKGROUND: One of the challenging tasks in systems biology is parameter estimation in nonlinear dynamic models. A biological model usually contains a large number of correlated parameters leading to non-identifiability problems. Although many approaches have been developed to address both structura...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015753/ https://www.ncbi.nlm.nih.gov/pubmed/24053643 http://dx.doi.org/10.1186/1752-0509-7-91 |