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The role of CXC-chemokine receptor CXCR2 and suppressor of cytokine signaling-3 (SOCS-3) in renal cell carcinoma

BACKGROUND: Chemokine receptor signaling pathways are implicated in the pathobiology of renal cell carcinoma (RCC). However, the clinical relevance of CXCR2 receptor, mediating the effects of all angiogenic chemokines, remains unclear. SOCS (suppressor of cytokine signaling)-3 is a negative regulato...

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Detalles Bibliográficos
Autores principales: Stofas, Anastasios, Levidou, Georgia, Piperi, Christina, Adamopoulos, Christos, Dalagiorgou, Georgia, Bamias, Aristotelis, Karadimou, Alexandra, Lainakis, George A, Papadoukakis, Stefanos, Stravodimos, Konstantinos, Dimopoulos, Meletios-Athanasios, Patsouris, Efstratios, Gakiopoulou, Hariklia, Korkolopoulou, Penelope
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015755/
https://www.ncbi.nlm.nih.gov/pubmed/24593195
http://dx.doi.org/10.1186/1471-2407-14-149