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Drug repurposing: a better approach for infectious disease drug discovery?

The advent of publicly available databases containing system-wide phenotypic data of the host response to both drugs and pathogens, in conjunction with bioinformatics and computational methods now allows for in silico predictions of FDA-approved drugs as treatments against infection diseases. This s...

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Detalles Bibliográficos
Autores principales: Law, G Lynn, Tisoncik-Go, Jennifer, Korth, Marcus J, Katze, Michael G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Ltd. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015799/
https://www.ncbi.nlm.nih.gov/pubmed/24011665
http://dx.doi.org/10.1016/j.coi.2013.08.004