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Inhibition of Raf-MEK-ERK and Hypoxia pathways by Phyllanthus prevents metastasis in human lung (A549) cancer cell line

BACKGROUND: Lung cancer constitutes one of the malignancies with the greatest incidence and mortality rates with 1.6 million new cases and 1.4 million deaths each year. Prognosis remains poor due to deleterious development of multidrug resistance resulting in less than 15% lung cancer patients reach...

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Detalles Bibliográficos
Autores principales: Lee, Sau Har, Jaganath, Indu Bala, Manikam, Rishya, Sekaran, Shamala Devi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015811/
https://www.ncbi.nlm.nih.gov/pubmed/24138815
http://dx.doi.org/10.1186/1472-6882-13-271