Cargando…
Inhibition of Raf-MEK-ERK and Hypoxia pathways by Phyllanthus prevents metastasis in human lung (A549) cancer cell line
BACKGROUND: Lung cancer constitutes one of the malignancies with the greatest incidence and mortality rates with 1.6 million new cases and 1.4 million deaths each year. Prognosis remains poor due to deleterious development of multidrug resistance resulting in less than 15% lung cancer patients reach...
Autores principales: | Lee, Sau Har, Jaganath, Indu Bala, Manikam, Rishya, Sekaran, Shamala Devi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015811/ https://www.ncbi.nlm.nih.gov/pubmed/24138815 http://dx.doi.org/10.1186/1472-6882-13-271 |
Ejemplares similares
-
Suppression of ERK1/2 and hypoxia pathways by four Phyllanthus species inhibits metastasis of human breast cancer cells
por: Lee, Sau H., et al.
Publicado: (2016) -
Inhibition of MAPKs, Myc/Max, NFκB, and Hypoxia Pathways by Phyllanthus Prevents Proliferation, Metastasis and Angiogenesis in Human Melanoma (MeWo) Cancer Cell Line
por: Tang, Yin-Quan, et al.
Publicado: (2014) -
Antimetastatic Effects of Phyllanthus on Human Lung (A549) and Breast (MCF-7) Cancer Cell Lines
por: Lee, Sau Har, et al.
Publicado: (2011) -
Phyllanthus Suppresses Prostate Cancer Cell, PC-3, Proliferation and Induces Apoptosis through Multiple Signalling Pathways (MAPKs, PI3K/Akt, NFκB, and Hypoxia)
por: Tang, Yin-Quan, et al.
Publicado: (2013) -
Evaluation of Antiviral Activities of Four Local Malaysian Phyllanthus Species against Herpes Simplex Viruses and Possible Antiviral Target
por: Tan, Wee Chee, et al.
Publicado: (2013)