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Perhexiline maleate in the treatment of fibrodysplasia ossificans progressiva: an open-labeled clinical trial

BACKGROUND: Currently, there are no effective medical treatment options to prevent the formation of heterotopic bones in fibrodysplasia ossificans progressiva (FOP). By the drug repositioning strategy, we confirmed that perhexiline maleate (Pex) potentially ameliorates heterotopic ossification in mo...

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Detalles Bibliográficos
Autores principales: Kitoh, Hiroshi, Achiwa, Masataka, Kaneko, Hiroshi, Mishima, Kenichi, Matsushita, Masaki, Kadono, Izumi, Horowitz, John D, Sallustio, Benedetta C, Ohno, Kinji, Ishiguro, Naoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015865/
https://www.ncbi.nlm.nih.gov/pubmed/24131551
http://dx.doi.org/10.1186/1750-1172-8-163