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Effects of Allium victorialis leaf extracts and its single compounds on aldose reductase, advanced glycation end products and TGF-β1 expression in mesangial cells

BACKGROUND: Accumulating evidences suggest that aldose reductase (AR) inhibitors and advanced glycation end product (AGE) formation inhibitors may prevent chronic hyperglycemia-induced long-term complication in diabetes. Transforming growth factor-beta1 (TGF-β1) plays an important role in the develo...

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Detalles Bibliográficos
Autores principales: Kim, Young Sook, Jung, Dong Ho, Lee, Ik Soo, Choi, So-Jin, Yu, Song Yi, Ku, Sea-Kwang, Kim, Myung-Hwa, Kim, Jin Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015874/
https://www.ncbi.nlm.nih.gov/pubmed/24090434
http://dx.doi.org/10.1186/1472-6882-13-251