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The Chromatin “Landscape” of a Murine Adult β-Globin Gene Is Unaffected by Deletion of Either the Gene Promoter or a Downstream Enhancer

In mammals, the complex tissue- and developmental-specific expression of genes within the β-globin cluster is known to be subject to control by the gene promoters, by a locus control region (LCR) located upstream of the cluster, and by sequence elements located across the intergenic regions. Despite...

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Detalles Bibliográficos
Autores principales: Cadiz-Rivera, Brenda, Fromm, George, de Vries, Christina, Fields, Jennifer, McGrath, Kathleen E., Fiering, Steven, Bulger, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015891/
https://www.ncbi.nlm.nih.gov/pubmed/24817273
http://dx.doi.org/10.1371/journal.pone.0092947