Degradation of AIMP1/p43 Induced by Hepatitis C Virus E2 Leads to Upregulation of TGF-β Signaling and Increase in Surface Expression of gp96

Hepatitis C virus (HCV) causes chronic hepatitis leading to liver fibrosis and autoimmune diseases. AIMP1/p43 is a multifunctional protein initially known as a cofactor of aminoacyl tRNA synthetase complex. Its function includes negative regulation of TGF-β signaling and suppression of Lupus-like au...

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Detalles Bibliográficos
Autores principales: Kim, Min Soo, Kim, Sunghoon, Myung, Heejoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015952/
https://www.ncbi.nlm.nih.gov/pubmed/24816397
http://dx.doi.org/10.1371/journal.pone.0096302

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015952/
https://www.ncbi.nlm.nih.gov/pubmed/24816397
http://dx.doi.org/10.1371/journal.pone.0096302

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