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Systematic design methodology for robust genetic transistors based on I/O specifications via promoter-RBS libraries

BACKGROUND: Synthetic genetic transistors are vital for signal amplification and switching in genetic circuits. However, it is still problematic to efficiently select the adequate promoters, Ribosome Binding Sides (RBSs) and inducer concentrations to construct a genetic transistor with the desired l...

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Detalles Bibliográficos
Autores principales: Lee, Yi-Ying, Hsu, Chih-Yuan, Lin, Ling-Jiun, Chang, Chih-Chun, Cheng, Hsiao-Chun, Yeh, Tsung-Hsien, Hu, Rei-Hsing, Lin, Che, Xie, Zhen, Chen, Bor-Sen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015965/
https://www.ncbi.nlm.nih.gov/pubmed/24160305
http://dx.doi.org/10.1186/1752-0509-7-109