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Systematic design methodology for robust genetic transistors based on I/O specifications via promoter-RBS libraries
BACKGROUND: Synthetic genetic transistors are vital for signal amplification and switching in genetic circuits. However, it is still problematic to efficiently select the adequate promoters, Ribosome Binding Sides (RBSs) and inducer concentrations to construct a genetic transistor with the desired l...
Autores principales: | Lee, Yi-Ying, Hsu, Chih-Yuan, Lin, Ling-Jiun, Chang, Chih-Chun, Cheng, Hsiao-Chun, Yeh, Tsung-Hsien, Hu, Rei-Hsing, Lin, Che, Xie, Zhen, Chen, Bor-Sen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015965/ https://www.ncbi.nlm.nih.gov/pubmed/24160305 http://dx.doi.org/10.1186/1752-0509-7-109 |
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