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Three steps to the immortality of cancer cells: senescence, polyploidy and self-renewal
Metastatic cancer is rarely cured by current DNA damaging treatments, apparently due to the development of resistance. However, recent data indicates that tumour cells can elicit the opposing processes of senescence and stemness in response to these treatments, the biological significance and molecu...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015969/ https://www.ncbi.nlm.nih.gov/pubmed/24025698 http://dx.doi.org/10.1186/1475-2867-13-92 |