Generation of Anti-Idiotype scFv for Pharmacokinetic Measurement in Lymphoma Patients Treated with Chimera Anti-CD22 Antibody SM03

Pre-clinical and clinical studies of therapeutic antibodies require highly specific reagents to examine their immune responses, bio-distributions, immunogenicity, and pharmacodynamics in patients. Selective antigen-mimicking anti-idiotype antibody facilitates the assessment of therapeutic antibody i...

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Detalles Bibliográficos
Autores principales: Zhao, Qi, Wong, Pui-Fan, Lee, Susanna S. T., Leung, Shui-On, Cheung, Wing-Tai, Wang, Jun-Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015983/
https://www.ncbi.nlm.nih.gov/pubmed/24816427
http://dx.doi.org/10.1371/journal.pone.0096697

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015983/
https://www.ncbi.nlm.nih.gov/pubmed/24816427
http://dx.doi.org/10.1371/journal.pone.0096697

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