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G(q) rather than G(11) preferentially mediates nociceptor sensitization

BACKGROUND: The G(q/11)-protein signaling mechanism is essential throughout the nervous system, but little is known about the contribution of the individual G-protein GPCR signaling branches towards nociceptor activation and their specific role on nociceptor sensitization. We aimed to unravel the co...

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Detalles Bibliográficos
Autores principales: Wirotanseng, Laura Nikita, Kuner, Rohini, Tappe-Theodor, Anke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016015/
https://www.ncbi.nlm.nih.gov/pubmed/24156378
http://dx.doi.org/10.1186/1744-8069-9-54