MicroRNA-7 Inhibits Tumor Metastasis and Reverses Epithelial-Mesenchymal Transition through AKT/ERK1/2 Inactivation by Targeting EGFR in Epithelial Ovarian Cancer

Epidermal growth factor receptor (EGFR) overexpression and activation result in increased proliferation and migration of solid tumors including ovarian cancer. In recent years, mounting evidence indicates that EGFR is a direct and functional target of miR-7. In this study, we found that miR-7 expres...

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Detalles Bibliográficos
Autores principales: Zhou, Xingchen, Hu, Yuan, Dai, Lan, Wang, Yunfei, Zhou, Jinhua, Wang, WenWen, Di, Wen, Qiu, Lihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016102/
https://www.ncbi.nlm.nih.gov/pubmed/24816687
http://dx.doi.org/10.1371/journal.pone.0096718

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016102/
https://www.ncbi.nlm.nih.gov/pubmed/24816687
http://dx.doi.org/10.1371/journal.pone.0096718

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