Deletion of CXCR4 in cardiomyocytes exacerbates cardiac dysfunction following isoproterenol administration

Altered alpha- and beta-adrenergic receptor signaling is associated with cardiac hypertrophy and failure. Stromal cell-derived factor-1α (SDF-1α) and its cognate receptor CXCR4 have been reported to mediate cardioprotection after injury through the mobilization of stem cells into injured tissue. How...

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Detalles Bibliográficos
Autores principales: Wang, ER, Jarrah, AA, Benard, L, Chen, J, Schwarzkopf, M, Hadri, L, Tarzami, ST
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016112/
https://www.ncbi.nlm.nih.gov/pubmed/24646609
http://dx.doi.org/10.1038/gt.2014.23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016112/
https://www.ncbi.nlm.nih.gov/pubmed/24646609
http://dx.doi.org/10.1038/gt.2014.23

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