Inhibition of K(+) Transport through Na(+), K(+)-ATPase by Capsazepine: Role of Membrane Span 10 of the α-Subunit in the Modulation of Ion Gating

Capsazepine (CPZ) inhibits Na(+),K(+)-ATPase-mediated K(+)-dependent ATP hydrolysis with no effect on Na(+)-ATPase activity. In this study we have investigated the functional effects of CPZ on Na(+),K(+)-ATPase in intact cells. We have also used well established biochemical and biophysical technique...

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Detalles Bibliográficos
Autores principales: Mahmmoud, Yasser A., Shattock, Michael, Cornelius, Flemming, Pavlovic, Davor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016139/
https://www.ncbi.nlm.nih.gov/pubmed/24816799
http://dx.doi.org/10.1371/journal.pone.0096909

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016139/
https://www.ncbi.nlm.nih.gov/pubmed/24816799
http://dx.doi.org/10.1371/journal.pone.0096909

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