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Integration of Molecular Profiling and Chemical Imaging to Elucidate Fibroblast-Microenvironment Impact on Cancer Cell Phenotype and Endocrine Resistance in Breast Cancer

The tumor microenvironment is known to play a key role in altering the properties and behavior of nearby cancer cells. Its influence on resistance to endocrine therapy and cancer relapse, however, is poorly understood. Here we investigate the interaction of mammary fibroblasts and estrogen receptor-...

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Detalles Bibliográficos
Autores principales: Holton, Sarah E., Bergamaschi, Anna, Katzenellenbogen, Benita S., Bhargava, Rohit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016150/
https://www.ncbi.nlm.nih.gov/pubmed/24816718
http://dx.doi.org/10.1371/journal.pone.0096878