Synapse elimination and learning rules coregulated by MHC Class I H2-Db

The formation of precise connections between retina and LGN involves the activity-dependent elimination of some synapses, with strengthening and retention of others. Here we show that the MHC Class I (MHCI) molecule H2-Db is necessary and sufficient for synapse elimination in the retinogeniculate sy...

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Detalles Bibliográficos
Autores principales: Lee, Hanmi, Kirkby, Lowry, Brott, Barbara K., Adelson, Jaimie D., Cheng, Sarah, Feller, Marla B., Datwani, Akash, Shatz, Carla J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016165/
https://www.ncbi.nlm.nih.gov/pubmed/24695230
http://dx.doi.org/10.1038/nature13154

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016165/
https://www.ncbi.nlm.nih.gov/pubmed/24695230
http://dx.doi.org/10.1038/nature13154

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