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Synapse elimination and learning rules coregulated by MHC Class I H2-Db
The formation of precise connections between retina and LGN involves the activity-dependent elimination of some synapses, with strengthening and retention of others. Here we show that the MHC Class I (MHCI) molecule H2-Db is necessary and sufficient for synapse elimination in the retinogeniculate sy...
Autores principales: | Lee, Hanmi, Kirkby, Lowry, Brott, Barbara K., Adelson, Jaimie D., Cheng, Sarah, Feller, Marla B., Datwani, Akash, Shatz, Carla J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016165/ https://www.ncbi.nlm.nih.gov/pubmed/24695230 http://dx.doi.org/10.1038/nature13154 |
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