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A Functional Variant of PTPN22 Confers Risk for Vogt-Koyanagi-Harada Syndrome but Not for Ankylosing Spondylitis

BACKGROUND: Protein tyrosine phosphatase non-receptor 22 (PTPN22) is a key negative regulator of T lymphocytes and has emerged as an important candidate susceptibility factor for a number of immune-related diseases. This study aimed to examine the predisposition of PTPN22 SNPs to Vogt-Koyanagi-Harad...

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Detalles Bibliográficos
Autores principales: Zhang, Qi, Qi, Jian, Hou, Shengping, Du, Liping, Yu, Hongsong, Cao, Qingfeng, Zhou, Yan, Liao, Dan, Kijlstra, Aize, Yang, Peizeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016172/
https://www.ncbi.nlm.nih.gov/pubmed/24816862
http://dx.doi.org/10.1371/journal.pone.0096943