LIM Domain Kinases as Potential Therapeutic Targets for Neurofibromatosis Type 2

Neurofibromatosis Type 2 (NF2) is caused by mutations in the neurofibromatosis 2 (NF2) gene that encodes a tumor suppressor protein called merlin. NF2 is characterized by formation of multiple schwannomas, meningiomas and ependymomas. Merlin loss of function is associated with increased activity of...

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Detalles Bibliográficos
Autores principales: Petrilli, Alejandra, Copik, Alicja, Posadas, Michelle, Chang, Long-Sheng, Welling, D. Bradley, Giovannini, Marco, Fernández-Valle, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016185/
https://www.ncbi.nlm.nih.gov/pubmed/23934191
http://dx.doi.org/10.1038/onc.2013.320

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016185/
https://www.ncbi.nlm.nih.gov/pubmed/23934191
http://dx.doi.org/10.1038/onc.2013.320

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