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REDD1 is essential for stress-induced synaptic loss and depressive behavior
Major depressive disorder (MDD) affects up to 17% of the population, causing profound personal suffering and economic loss (1). Clinical and pre-clinical studies have revealed that prolonged stress and MDD are associated with neuronal atrophy of cortical and limbic brain regions (2-9), but the molec...
Autores principales: | Ota, Kristie T., Liu, Rong-Jian, Voleti, Bhavya, Maldonado-Aviles, Jaime G., Duric, Vanja, Iwata, Masaaki, Dutheil, Sophie, Duman, Catharine, Boikess, Steve, Lewis, David A., Stockmeier, Craig A., DiLeone, Ralph J., Rex, Christopher, Aghajanian, George K., Duman, Ronald S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016190/ https://www.ncbi.nlm.nih.gov/pubmed/24728411 http://dx.doi.org/10.1038/nm.3513 |
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