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Clinical, Immunological and Treatment-Related Factors Associated with Normalised CD4+/CD8+ T-Cell Ratio: Effect of Naïve and Memory T-Cell Subsets

BACKGROUND: Although effective antiretroviral therapy(ART) increases CD4+ T-cell count, responses to ART vary considerably and only a minority of patients normalise their CD4+/CD8+ ratio. Although retention of naïve CD4+ T-cells is thought to predict better immune responses, relationships between CD...

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Detalles Bibliográficos
Autores principales: Tinago, Willard, Coghlan, Elizabeth, Macken, Alan, McAndrews, Julie, Doak, Brenda, Prior-Fuller, Charlotte, Lambert, John S., Sheehan, Gerard J., Mallon, Patrick W. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016205/
https://www.ncbi.nlm.nih.gov/pubmed/24816636
http://dx.doi.org/10.1371/journal.pone.0097011