Aurora-A Mitotic Kinase Induces Endocrine Resistance through Down-Regulation of ERα Expression in Initially ERα+ Breast Cancer Cells

Development of endocrine resistance during tumor progression represents a major challenge in the management of estrogen receptor alpha (ERα) positive breast tumors and is an area under intense investigation. Although the underlying mechanisms are still poorly understood, many studies point towards t...

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Detalles Bibliográficos
Autores principales: Opyrchal, Mateusz, Salisbury, Jeffrey L., Zhang, Shuya, McCubrey, James, Hawse, John, Goetz, Mattew P., Lomberk, Gwen A., Haddad, Tufia, Degnim, Amy, Lange, Carol, Ingle, James N., Galanis, Evanthia, D'Assoro, Antonino B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016211/
https://www.ncbi.nlm.nih.gov/pubmed/24816249
http://dx.doi.org/10.1371/journal.pone.0096995

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016211/
https://www.ncbi.nlm.nih.gov/pubmed/24816249
http://dx.doi.org/10.1371/journal.pone.0096995

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