Inhibition of cancer cell proliferation and apoptosis-inducing activity of fungal taxol and its precursor baccatin III purified from endophytic Fusarium solani

BACKGROUND: Taxol (generic name paclitaxel), a plant-derived antineoplastic agent, used widely against breast, ovarian and lung cancer, was originally isolated from the bark of the Pacific yew, Taxus brevifolia. The limited supply of the drug has prompted efforts to find alternative sources, such as...

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Detalles Bibliográficos
Autores principales: Chakravarthi, Balabhadrapatruni VSK, Sujay, Ramanathan, Kuriakose, Gini C, Karande, Anjali A, Jayabaskaran, Chelliah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016216/
https://www.ncbi.nlm.nih.gov/pubmed/24152585
http://dx.doi.org/10.1186/1475-2867-13-105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016216/
https://www.ncbi.nlm.nih.gov/pubmed/24152585
http://dx.doi.org/10.1186/1475-2867-13-105

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