N-Acetyl-Heparin Attenuates Acute Lung Injury Caused by Acid Aspiration Mainly by Antagonizing Histones in Mice

Acute lung injury (ALI) is the leading cause of death in intensive care units. Extracellular histones have recently been recognized to be pivotal inflammatory mediators. Heparin and its derivatives can bind histones through electrostatic interaction. The purpose of this study was to investigate 1) t...

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Detalles Bibliográficos
Autores principales: Zhang, Yanlin, Zhao, Zanmei, Guan, Li, Mao, Lijun, Li, Shuqiang, Guan, Xiaoxu, Chen, Ming, Guo, Lixia, Ding, Lihua, Cong, Cuicui, Wen, Tao, Zhao, Jinyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016230/
https://www.ncbi.nlm.nih.gov/pubmed/24816808
http://dx.doi.org/10.1371/journal.pone.0097074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016230/
https://www.ncbi.nlm.nih.gov/pubmed/24816808
http://dx.doi.org/10.1371/journal.pone.0097074

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