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Predictive value of in vitro assays depends on the mechanism of toxicity of metal oxide nanoparticles
BACKGROUND: Hazard identification for risk assessment of nanoparticles (NPs) is mainly composed of in vitro cell-based assays and in vivo animal experimentation. The rapidly increasing number and functionalizations of NPs makes in vivo toxicity tests undesirable on both ethical and financial grounds...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016420/ https://www.ncbi.nlm.nih.gov/pubmed/24156363 http://dx.doi.org/10.1186/1743-8977-10-55 |