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Predictive value of in vitro assays depends on the mechanism of toxicity of metal oxide nanoparticles

BACKGROUND: Hazard identification for risk assessment of nanoparticles (NPs) is mainly composed of in vitro cell-based assays and in vivo animal experimentation. The rapidly increasing number and functionalizations of NPs makes in vivo toxicity tests undesirable on both ethical and financial grounds...

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Detalles Bibliográficos
Autores principales:	Cho, Wan-Seob, Duffin, Rodger, Bradley, Mark, Megson, Ian L, MacNee, William, Lee, Jong Kwon, Jeong, Jayoung, Donaldson, Ken
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016420/ https://www.ncbi.nlm.nih.gov/pubmed/24156363 http://dx.doi.org/10.1186/1743-8977-10-55

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