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Genetic polymorphisms in plasminogen activator inhibitor-1 predict susceptibility to steroid-induced osteonecrosis of the femoral head in Chinese population

BACKGROUND: Steroid usage has been considered as a leading cause of non-traumatic osteonecrosis of the femoral head (ONFH), which is involved in hypo-fibrinolysis and blood supply interruption. Genetic polymorphisms in plasminogen activator inhibitor-1 (PAI-1) have been demonstrated to be associated...

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Detalles Bibliográficos
Autores principales: Zhang, Yanqiong, Wang, Rongtian, Li, Shangzhu, Kong, Xiangying, Wang, Zhiyao, Chen, Weiheng, Lin, Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016530/
https://www.ncbi.nlm.nih.gov/pubmed/24135164
http://dx.doi.org/10.1186/1746-1596-8-169