Cargando…

Differential recruitment of coregulators to the RORA promoter adds another layer of complexity to gene (dys) regulation by sex hormones in autism

BACKGROUND: Our independent cohort studies have consistently shown the reduction of the nuclear receptor RORA (retinoic acid-related orphan receptor-alpha) in lymphoblasts as well as in brain tissues from individuals with autism spectrum disorder (ASD). Moreover, we have found that RORA regulates th...

Descripción completa

Detalles Bibliográficos
Autores principales: Sarachana, Tewarit, Hu, Valerie W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016566/
https://www.ncbi.nlm.nih.gov/pubmed/24119295
http://dx.doi.org/10.1186/2040-2392-4-39