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Genomic profiling of type-1 adult diabetic and aged normoglycemic mouse liver

BACKGROUND: Hyperglycemia induces chromatin remodeling with consequences on differential gene expression in mouse hepatocytes, similar to what occurs during aging. The liver is the central organ for the regulation of glucose homeostasis and xenobiotic and lipid metabolism and is affected by insulin...

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Detalles Bibliográficos
Autores principales: Ghiraldini, Flávia G, Silveira, André B, Kleinjan, Dirk A, Gilbert, Nick, Mello, Maria Luiza S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016577/
https://www.ncbi.nlm.nih.gov/pubmed/24581510
http://dx.doi.org/10.1186/1472-6823-14-19