Defining structural and evolutionary modules in proteins: a community detection approach to explore sub-domain architecture

BACKGROUND: Assessing protein modularity is important to understand protein evolution. Still the question of the existence of a sub-domain modular architecture remains. We propose a graph-theory approach with significance and power testing to identify modules in protein structures. In the first step...

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Detalles Bibliográficos
Autores principales: Hleap, Jose Sergio, Susko, Edward, Blouin, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016585/
https://www.ncbi.nlm.nih.gov/pubmed/24131821
http://dx.doi.org/10.1186/1472-6807-13-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016585/
https://www.ncbi.nlm.nih.gov/pubmed/24131821
http://dx.doi.org/10.1186/1472-6807-13-20

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