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Defining structural and evolutionary modules in proteins: a community detection approach to explore sub-domain architecture
BACKGROUND: Assessing protein modularity is important to understand protein evolution. Still the question of the existence of a sub-domain modular architecture remains. We propose a graph-theory approach with significance and power testing to identify modules in protein structures. In the first step...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016585/ https://www.ncbi.nlm.nih.gov/pubmed/24131821 http://dx.doi.org/10.1186/1472-6807-13-20 |