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Inferring the effective TOR-dependent network: a computational study in yeast

BACKGROUND: Calorie restriction (CR) is one of the most conserved non-genetic interventions that extends healthspan in evolutionarily distant species, ranging from yeast to mammals. The target of rapamycin (TOR) has been shown to play a key role in mediating healthspan extension in response to CR by...

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Detalles Bibliográficos
Autores principales: Mohammadi, Shahin, Subramaniam, Shankar, Grama, Ananth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016608/
https://www.ncbi.nlm.nih.gov/pubmed/24005029
http://dx.doi.org/10.1186/1752-0509-7-84