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Inferring the effective TOR-dependent network: a computational study in yeast
BACKGROUND: Calorie restriction (CR) is one of the most conserved non-genetic interventions that extends healthspan in evolutionarily distant species, ranging from yeast to mammals. The target of rapamycin (TOR) has been shown to play a key role in mediating healthspan extension in response to CR by...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016608/ https://www.ncbi.nlm.nih.gov/pubmed/24005029 http://dx.doi.org/10.1186/1752-0509-7-84 |