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Clusterin silencing inhibits proliferation and reduces invasion in human laryngeal squamous carcinoma cells

BACKGROUND: Clusterin is, in its major form, a secreted heterodimeric disulfide-linked glycoprotein (sCLU), which plays important roles in cell survival and death. In laryngeal squamous cell carcinomas (LSCC), sCLU is up-regulated and its expression is related to the invasiveness of these tumors. Th...

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Detalles Bibliográficos
Autores principales: Wang, Qianjin, Cao, Weiyan, Su, Quancai, Liu, Zimin, Zhang, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016627/
https://www.ncbi.nlm.nih.gov/pubmed/24767179
http://dx.doi.org/10.1186/1477-7819-12-124