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Clusterin silencing inhibits proliferation and reduces invasion in human laryngeal squamous carcinoma cells
BACKGROUND: Clusterin is, in its major form, a secreted heterodimeric disulfide-linked glycoprotein (sCLU), which plays important roles in cell survival and death. In laryngeal squamous cell carcinomas (LSCC), sCLU is up-regulated and its expression is related to the invasiveness of these tumors. Th...
Autores principales: | Wang, Qianjin, Cao, Weiyan, Su, Quancai, Liu, Zimin, Zhang, Lin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016627/ https://www.ncbi.nlm.nih.gov/pubmed/24767179 http://dx.doi.org/10.1186/1477-7819-12-124 |
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