Cas-OFFinder: a fast and versatile algorithm that searches for potential off-target sites of Cas9 RNA-guided endonucleases

Summary: The Type II clustered regularly interspaced short palindromic repeats (CRISPR)/Cas system is an adaptive immune response in prokaryotes, protecting host cells against invading phages or plasmids by cleaving these foreign DNA species in a targeted manner. CRISPR/Cas-derived RNA-guided engine...

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Detalles Bibliográficos
Autores principales: Bae, Sangsu, Park, Jeongbin, Kim, Jin-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Applications Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016707/
https://www.ncbi.nlm.nih.gov/pubmed/24463181
http://dx.doi.org/10.1093/bioinformatics/btu048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016707/
https://www.ncbi.nlm.nih.gov/pubmed/24463181
http://dx.doi.org/10.1093/bioinformatics/btu048

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