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FOXO Transcription Factors: Their Clinical Significance and Regulation

Members of the class O of forkhead box transcription factors (FOXO) have important roles in metabolism, cellular proliferation, stress resistance, and apoptosis. The activity of FOXOs is tightly regulated by posttranslational modification, including phosphorylation, acetylation, and ubiquitylation....

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Detalles Bibliográficos
Autores principales: Wang, Yu, Zhou, Yanmin, Graves, Dana T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016844/
https://www.ncbi.nlm.nih.gov/pubmed/24864265
http://dx.doi.org/10.1155/2014/925350