Syn-Lethality: An Integrative Knowledge Base of Synthetic Lethality towards Discovery of Selective Anticancer Therapies

Synthetic lethality (SL) is a novel strategy for anticancer therapies, whereby mutations of two genes will kill a cell but mutation of a single gene will not. Therefore, a cancer-specific mutation combined with a drug-induced mutation, if they have SL interactions, will selectively kill cancer cells...

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Detalles Bibliográficos
Autores principales: Li, Xue-juan, Mishra, Shital K., Wu, Min, Zhang, Fan, Zheng, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016865/
https://www.ncbi.nlm.nih.gov/pubmed/24864230
http://dx.doi.org/10.1155/2014/196034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016865/
https://www.ncbi.nlm.nih.gov/pubmed/24864230
http://dx.doi.org/10.1155/2014/196034

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