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Upregulated PD-1 Expression Is Associated with the Development of Systemic Lupus Erythematosus, but Not the PD-1.1 Allele of the PDCD1 Gene

Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease with complicated genetic inheritance. Programmed death 1 (PD-1), a negative T cell regulator to maintain peripheral tolerance, induces negative signals to T cells during interaction with its ligands and is therefore a candidate g...

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Detalles Bibliográficos
Autores principales: Jiao, Qingqing, Liu, Cuiping, Yang, Ziliang, Ding, Qiang, Wang, Miaomiao, Li, Min, Zhu, Tingting, Qian, Hua, Li, Wei, Tu, Na, Fang, Fumin, Ye, Licai, Zhao, Zuotao, Qian, Qihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016872/
https://www.ncbi.nlm.nih.gov/pubmed/24860805
http://dx.doi.org/10.1155/2014/950903