Synthesis and Biological Evaluation of 2,4-Diaminopyrimidine-Based Antifolate Drugs against Bacillus anthracis

Due to the innate ability of bacteria to develop resistance to available antibiotics, there is a critical need to develop new agents to treat more resilient strains. As a continuation of our research in this area, we have synthesized a series of racemic 2,4-diaminopyrimidine-based drug candidates, a...

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Detalles Bibliográficos
Autores principales: Nammalwar, Baskar, Muddala, N. Prasad, Bourne, Christina R., Henry, Mary, Bourne, Philip C., Bunce, Richard A., Barrow, Esther W., Berlin, K. Darrell, Barrow, William W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016962/
https://www.ncbi.nlm.nih.gov/pubmed/24642909
http://dx.doi.org/10.3390/molecules19033231

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016962/
https://www.ncbi.nlm.nih.gov/pubmed/24642909
http://dx.doi.org/10.3390/molecules19033231

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