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A role for eukaryotic initiation factor 4B overexpression in the pathogenesis of diffuse large B-cell lymphoma

Dysregulated expression of factors that control protein synthesis is associated with poor prognosis of many cancers, but the underlying mechanisms are not well defined. Analysis of the diffuse large B-cell lymphoma (DLBCL) translatome revealed selective upregulation of mRNAs encoding anti-apoptotic...

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Detalles Bibliográficos
Autores principales: Horvilleur, E, Sbarrato, T, Hill, K, Spriggs, R V, Screen, M, Goodrem, P J, Sawicka, K, Chaplin, L C, Touriol, C, Packham, G, Potter, K N, Dirnhofer, S, Tzankov, A, Dyer, M J S, Bushell, M, MacFarlane, M, Willis, A E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017261/
https://www.ncbi.nlm.nih.gov/pubmed/24135829
http://dx.doi.org/10.1038/leu.2013.295